When I was brought on as Creative Director for Demand by Design, my job consisted of a mountain of work for our clients. However, I knew that the two principals were not happy with our own web presence.
5 months after I started, I saw some breathing room and fired up Photoshop to develop a color palette and look and feel for our new site. Within a week, I had a design that they liked and over one weekend I had it up and running on WordPress. I used the Starkers framework and created a completely custom design based on what I had created in Photoshop.
Adobe Photoshop Creative Direction CSS Custom WordPress Theme Development HTML